Basic Information
ID: ALA5162312
Type: Binding
Description: Potency index, ratio of test compound IC50 to pyrotinib IC50 for inhibition of wild type human GST-tagged HER2 (676 to end residues) expressed in baculovirus infected Sf9 cells incubated for 30 mins in presence of ATP by HTRF analysis
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA5162312
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 583.63 | 5.20 | 5.20 |
| 482.50 | 4.44 | 4.44 |
| 583.63 | 5.20 | 5.20 |
| 536.60 | 4.81 | 4.81 |
| 583.63 | 5.20 | 5.20 |
| 521.59 | 4.50 | 4.50 |
| 536.60 | 4.81 | 4.81 |
| 583.63 | 5.20 | 5.20 |
| 500.49 | 4.73 | 4.73 |
| 565.64 | 4.90 | 4.90 |
| 536.60 | 4.81 | 4.81 |
| 535.61 | 5.42 | 5.42 |
| 536.60 | 4.81 | 4.81 |
| 535.61 | 5.42 | 5.42 |
| 537.58 | 4.21 | 4.21 |