Basic Information
ID: ALA5162360
Type: Functional
Description: Antitumor activity against mouse BaF3 cells harbouring HER2 A775_G776insYVMA mutant xenografted in BALB/c nude mouse assessed as tumor growth inhibition at 20 mg/kg, po qd measured for 13 days relative to control
Organism: Mus musculus
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA5162360
TGI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 557.05 | 5.93 | 5.93 |
| 583.09 | 6.47 | 6.47 |
| 583.63 | 5.20 | 5.20 |