Assay Report Card

Basic Information

ID: ALA5162364

Type: Toxicity

Description: Toxicity in BALB/c nude mouse xenografted with mouse BaF3 cells harbouring HER2 A775_G776insYVMA mutant assessed as reduction in body weight at 10 to 40 mg/kg, po qd for 13 days

Organism: Mus musculus

Strain: BALB/c

Cell type: BaF3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
583.635.205.20