Basic Information
ID: ALA5162378
Type: Binding
Description: Potency index, ratio of pyrotinib IC50 to test compound IC50 for inhibition of HER2 V777L mutant (unknown origin) incubated for 120 mins in presence of 33P-ATP by P81 ion exchange cellulose chromatography
Format: BAO_0000357
Organism: Homo sapiens
Target: Receptor protein-tyrosine kinase erbB-2(ALA1824)
Document: ALA5154811
Potency index, ratio of pyrotinib IC50 to test compound IC50 for inhibition of HER2 V777L mutant (unknown origin) incubated for 120 mins in presence of 33P-ATP by P81 ion exchange cellulose chromatography: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5162378
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 583.63 | 5.20 | 5.20 |