Basic Information
ID: ALA5162482
Type: ADME
Description: Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 10 mins followed by NADPH addition and measured after 10 mins by LC/MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5162482
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.40 | 2.48 | 2.48 |
| 414.51 | 3.74 | 3.74 |
| 372.43 | 2.72 | 2.72 |
| 627.58 | 4.20 | 4.20 |
| 448.53 | 3.94 | 3.94 |