Basic Information
ID: ALA5162941
Type: Binding
Description: Inhibition of AChE in mouse cerebral cortex using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition and measured for 180 secs by Ellman's spectrophotometric method
Format: BAO_0000221
Organism: Mus musculus
Tissue: Cerebral cortex
Target: Acetylcholinesterase(ALA3198)
Document: ALA5154822
Inhibition of AChE in mouse cerebral cortex using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition and measured for 180 secs by Ellman's spectrophotometric method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5162941
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.50 | 4.36 | 4.36 |
| 469.53 | 4.12 | 4.12 |
| 431.55 | 3.88 | 3.88 |
| 467.99 | 4.45 | 4.45 |
| 451.54 | 3.98 | 3.98 |
| 467.99 | 4.50 | 4.50 |
| 447.57 | 4.11 | 4.11 |
| 451.54 | 4.14 | 4.14 |
| 433.55 | 3.84 | 3.84 |
| 433.55 | 3.84 | 3.84 |
| 413.54 | 3.83 | 3.83 |
| 451.54 | 3.94 | 3.94 |
| 413.54 | 4.13 | 4.13 |
| 433.55 | 3.84 | 3.84 |
| 501.54 | 4.82 | 4.82 |
| 427.57 | 4.22 | 4.22 |
| 447.57 | 4.11 | 4.11 |
| 451.54 | 3.94 | 3.94 |
| 413.54 | 3.83 | 3.83 |
| 451.54 | 3.94 | 3.94 |
| 415.56 | 3.70 | 3.70 |
| 469.53 | 4.07 | 4.07 |
| 433.55 | 3.80 | 3.80 |
| 485.98 | 4.59 | 4.59 |
| 467.99 | 4.45 | 4.45 |
| 435.97 | 4.47 | 4.47 |
| 401.53 | 3.90 | 3.90 |