Assay Report Card

Basic Information

ID: ALA5162957

Type: ADME

Description: Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins followed by NADPH addition and measured after 10 mins by LC-MS/MS analysis

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
488.004.144.14