Basic Information
ID: ALA5163165
Type: Functional
Description: Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of GLP-1(7-36)NH2 induced cAMP accumulation at 10 uM preincubated for 15 mins followed by GLP-1(7-36)NH2 addition and measured after 15 mins relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5163165
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.54 | 4.16 | 4.16 |
| 526.51 | 4.00 | 4.00 |
| 452.91 | 5.14 | 5.14 |
| 446.90 | 3.30 | 3.30 |
| 500.93 | 4.35 | 4.35 |
| 589.43 | 4.72 | 4.72 |
| 498.50 | 4.09 | 4.09 |
| 496.51 | 3.71 | 3.71 |
| 390.79 | 2.45 | 2.45 |
| 410.44 | 3.30 | 3.30 |