Assay Report Card

Basic Information

ID: ALA5163168

Type: Binding

Description: Positive allosteric modulator activity at GLP-1R in rat INS1 beta-cells assessed potentiation of GLP-1(7-36)NH2 induced insulin secretion at 1 uM incubated for 30 mins in presence of 15 mM of glucose by ELISA

Organism: Rattus norvegicus

Cell type: INS1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
452.915.145.14
446.903.303.30
390.792.452.45
410.443.303.30