Basic Information
ID: ALA5163232
Type: Binding
Description: Inhibition of PRC2 (unknown origin) assessed as reduction in H3K27 trimethylation using H3K27Me0 peptide (21 to 44 residues) as substrate by measuring SAH formation by LC-MS analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA5154826
Inhibition of PRC2 (unknown origin) assessed as reduction in H3K27 trimethylation using H3K27Me0 peptide (21 to 44 residues) as substrate by measuring SAH formation by LC-MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5163232
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.41 | 2.40 | 2.40 |
| 376.40 | 3.18 | 3.18 |
| 402.46 | 3.19 | 3.19 |
| 400.49 | 3.40 | 3.40 |
| 378.41 | 3.56 | 3.56 |
| 400.49 | 3.40 | 3.40 |
| 377.42 | 4.17 | 4.17 |
| 344.38 | 2.73 | 2.73 |
| 349.37 | 3.55 | 3.55 |
| 390.42 | 3.49 | 3.49 |
| 376.40 | 3.18 | 3.18 |
| 363.40 | 3.86 | 3.86 |
| 362.37 | 2.87 | 2.87 |
| 388.48 | 3.47 | 3.47 |
| 344.38 | 2.73 | 2.73 |