Basic Information
ID: ALA5163246
Type: ADME
Description: Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Cytochrome P450 2C9(ALA3397)
Document: ALA5154826
Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5163246
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.41 | 2.40 | 2.40 |
| 376.40 | 3.18 | 3.18 |
| 378.41 | 3.56 | 3.56 |
| 344.38 | 2.73 | 2.73 |
| 344.38 | 2.73 | 2.73 |