Basic Information
ID: ALA5163481
Type: Binding
Description: Inhibition of TDO in human HEK293 cells assessed as reduction in kynurenine formation using L-tryptophan as substrate by absorbance based analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5163481
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 310.35 | 3.22 | 3.22 |
| 310.35 | 3.43 | 3.43 |
| 438.24 | 0.42 | 0.42 |
| 322.32 | 2.69 | 2.69 |
| 391.42 | 3.68 | 3.68 |
| 324.31 | 3.67 | 3.67 |
| 324.33 | 2.61 | 2.61 |
| 340.76 | 3.94 | 3.94 |
| 336.30 | 2.90 | 2.90 |
| 352.39 | 3.79 | 3.79 |
| 324.33 | 2.86 | 2.86 |
| 306.32 | 3.51 | 3.51 |
| 326.35 | 2.40 | 2.40 |
| 368.39 | 2.97 | 2.97 |
| 368.39 | 2.97 | 2.97 |
| 373.25 | 5.14 | 5.14 |
| 308.33 | 3.43 | 3.43 |
| 322.32 | 3.55 | 3.55 |
| 388.44 | 3.20 | 3.20 |
| 364.35 | 3.26 | 3.26 |
| 366.37 | 3.18 | 3.18 |