Assay Report Card

Basic Information

ID: ALA5163579

Type: Functional

Description: Invivo antagonist activity at V2R in Pkd1 knockout mouse model of autosomal dominant polycystic kidney disease assessed as reduction in kidney size at 2 mg/kg, sc administered once daily treatment started from postnatal day 6 to 12 days

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
448.955.685.68
561.135.615.61
589.186.396.39
561.177.017.01
575.156.006.00
588.205.925.92
603.216.786.78
567.137.317.31
573.187.167.16
589.145.535.53