Basic Information
ID: ALA5164199
Type: Binding
Description: PROTAC activity at CRBN/BRD4 in human MV4-11 cells assessed as induction of BRD4 degradation at 1 to 10 uM measured after 24 hrs by western blot analysis
Organism: Homo sapiens
Cell type: MV4-11
Activity Charts
Bioactivity
Activity Types for Assay ALA5164199
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 844.35 | 5.69 | 5.69 |
| 642.14 | 4.59 | 4.59 |
| 1006.54 | ||
| 872.41 | 6.47 | 6.47 |
| 962.49 | 5.35 | 5.35 |
| 830.33 | 5.30 | 5.30 |
| 874.38 | 5.31 | 5.31 |
| 914.49 | 7.64 | 7.64 |
| 900.46 | 7.25 | 7.25 |
| 918.43 | 5.33 | 5.33 |