Basic Information
ID: ALA5164253
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed mouse BMDM cells assessed as reduction in IL-1beta level at 1 uM pre-treated for 15 mins followed by ATP stimulation for 30 mins by ELISA relative to control
Organism: Mus musculus
Cell type: BMDM
Activity Charts
Bioactivity
Activity Types for Assay ALA5164253
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 404.49 | 2.99 | 2.99 |
| 434.45 | 3.26 | 3.26 |
| 406.39 | 2.03 | 2.03 |
| 376.37 | 2.03 | 2.03 |
| 392.35 | 1.93 | 1.93 |
| 386.41 | 2.51 | 2.51 |
| 374.39 | 2.63 | 2.63 |
| 360.37 | 2.33 | 2.33 |
| 360.37 | 2.33 | 2.33 |
| 389.41 | 2.08 | 2.08 |
| 390.35 | 1.75 | 1.75 |
| 376.37 | 2.03 | 2.03 |
| 434.45 | 3.59 | 3.59 |
| 360.37 | 2.33 | 2.33 |
| 448.78 | 3.69 | 3.69 |