Assay Report Card

Basic Information

ID: ALA5164279

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in LPS-primed mouse BMDM cells assessed as inhibition of caspase-1 cleavage in supernatant at 1 uM pretreated for 15 mins followed by ATP addition for 30 mins by Western blot analysis

Organism: Mus musculus

Cell type: BMDM

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
374.392.632.63