ID: ALA5164473
Type: Binding
Description: Inhibition of wild type HIV1 protease expressed in Escherichia coli BL21 DE3 assessed as cleavage of fluorogenic substrate using EDANS-RESGIFLETSKR-DABCYL preincubated for 15 mins with compound followed by substrate addition and measured after 60 mins by microplate reader analysis
Format: BAO_0000019
Organism: Human immunodeficiency virus 1
Target: Human immunodeficiency virus type 1 protease(ALA243)
Document: ALA5154858
Inhibition of wild type HIV1 protease expressed in Escherichia coli BL21 DE3 assessed as cleavage of fluorogenic substrate using EDANS-RESGIFLETSKR-DABCYL preincubated for 15 mins with compound followed by substrate addition and measured after 60 mins by microplate reader analysis: 1
Bioactivity
Activity Types for Assay ALA5164473
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
417.53 | 2.54 | 2.54 |
483.56 | 3.12 | 3.12 |
445.58 | 3.18 | 3.18 |
483.56 | 3.12 | 3.12 |
431.55 | 2.79 | 2.79 |
503.66 | 3.96 | 3.96 |
519.66 | 2.94 | 2.94 |