Inhibition of wild type HIV1 protease expressed in Escherichia coli BL21 DE3 assessed as cleavage of fluorogenic substrate using EDANS-RESGIFLETSKR-DA...

Basic Information

ID: ALA5164473

Type: Binding

Description: Inhibition of wild type HIV1 protease expressed in Escherichia coli BL21 DE3 assessed as cleavage of fluorogenic substrate using EDANS-RESGIFLETSKR-DABCYL preincubated for 15 mins with compound followed by substrate addition and measured after 60 mins by microplate reader analysis

Format: BAO_0000019

Organism: Human immunodeficiency virus 1

Target:  Human immunodeficiency virus type 1 protease(ALA243)

Document:  ALA5154858

Inhibition of wild type HIV1 protease expressed in Escherichia coli BL21 DE3 assessed as cleavage of fluorogenic substrate using EDANS-RESGIFLETSKR-DABCYL preincubated for 15 mins with compound followed by substrate addition and measured after 60 mins by microplate reader analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
417.532.542.54
483.563.123.12
445.583.183.18
483.563.123.12
431.552.792.79
503.663.963.96
519.662.942.94