Basic Information
ID: ALA5164917
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse J774.A1 cells assessed as reduction in pyroptosis pretreated for 4 hrs with LPS and for 30 mins with compound prior to ATP addition and measured after 30 mins by PI/Hoechst33342 staining based analysis
Organism: Mus musculus
Cell type: J774.A1
Activity Charts
Bioactivity
Activity Types for Assay ALA5164917
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.42 | 4.97 | 4.97 |