Basic Information
ID: ALA5164918
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated C57BL/6 mouse bone marrow-derived macrophages assessed as reduction in activated caspase 1(P20) level in culture supernatants preincubated for 3 hrs with LPS and for 30 mins with compound prior to nigericin addition and measured after 30 mins by Western blot analysis
Organism: Mus musculus
Cell type: BMDM
Activity Charts
Bioactivity
Activity Types for Assay ALA5164918
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.42 | 4.97 | 4.97 |