Assay Report Card

Basic Information

ID: ALA5164922

Type: Functional

Description: Effect on NLRP3 expression in cell lysates of LPS/nigericin-stimulated C57BL/6 mouse bone marrow-derived macrophages at 0.5 to 2 uM preincubated for 3 hrs with LPS and for 30 mins with compound prior to nigericin addition and measured after 30 mins by Western blot analysis

Organism: Mus musculus

Strain: C57BL/6

Subcellular Fraction: Lysates

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
420.424.974.97