Assay Report Card

Basic Information

ID: ALA5164941

Type: Binding

Description: Inhibition of AIM2 inflammasome activation in LPS/poly-(dA:dT)-treated C57BL/6 mouse bone marrow-derived macrophages assessed as reduction in IL-1beta secretion preincubated for 3 hrs with LPS and for 30 mins with compound prior to poly-(dA:dT) addition and measured after 30 mins by ELISA

Organism: Mus musculus

Strain: C57BL/6

Cell type: BMDM

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
420.424.974.97