ID: ALA5164941
Type: Binding
Description: Inhibition of AIM2 inflammasome activation in LPS/poly-(dA:dT)-treated C57BL/6 mouse bone marrow-derived macrophages assessed as reduction in IL-1beta secretion preincubated for 3 hrs with LPS and for 30 mins with compound prior to poly-(dA:dT) addition and measured after 30 mins by ELISA
Organism: Mus musculus
Strain: C57BL/6
Cell type: BMDM
Bioactivity
Activity Types for Assay ALA5164941
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
420.42 | 4.97 | 4.97 |