Basic Information
ID: ALA5165028
Type: Binding
Description: Inhibition of Cathepsin C in human THP-1 cells using H-Gly-Phe-AFC as substrate pretreated for 1 hr followed by substrate addition and incubated for 60 mins by microplate reader assay
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5165028
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.47 | 1.73 | 1.73 |
| 447.87 | 6.76 | 6.76 |
| 443.45 | 6.11 | 6.11 |
| 427.46 | 6.41 | 6.41 |
| 431.42 | 6.25 | 6.25 |
| 531.56 | 7.98 | 7.98 |
| 447.87 | 6.76 | 6.76 |
| 479.49 | 7.37 | 7.37 |
| 448.86 | 6.15 | 6.15 |
| 490.51 | 7.17 | 7.17 |
| 448.86 | 6.15 | 6.15 |
| 465.86 | 6.90 | 6.90 |
| 504.54 | 7.36 | 7.36 |
| 567.62 | 7.18 | 7.18 |
| 493.52 | 6.51 | 6.51 |
| 380.86 | 5.14 | 5.14 |
| 431.81 | 6.29 | 6.29 |
| 447.87 | 6.76 | 6.76 |
| 463.87 | 6.64 | 6.64 |
| 394.89 | 5.32 | 5.32 |
| 523.97 | 8.43 | 8.43 |
| 397.87 | 5.88 | 5.88 |
| 601.70 | 7.52 | 7.52 |
| 532.55 | 6.87 | 6.87 |
| 436.93 | 5.70 | 5.70 |
| 386.91 | 4.16 | 4.16 |
| 463.87 | 6.64 | 6.64 |
| 489.53 | 7.77 | 7.77 |
| 446.89 | 7.36 | 7.36 |
| 446.89 | 7.36 | 7.36 |
| 508.57 | 6.83 | 6.83 |
| 394.89 | 5.32 | 5.32 |
| 587.67 | 7.52 | 7.52 |
| 448.86 | 6.15 | 6.15 |
| 415.86 | 6.02 | 6.02 |
| 436.93 | 5.70 | 5.70 |
| 447.87 | 6.76 | 6.76 |
| 546.58 | 7.73 | 7.73 |
| 461.90 | 6.63 | 6.63 |
| 447.87 | 6.76 | 6.76 |
| 492.32 | 6.87 | 6.87 |
| 523.97 | 8.43 | 8.43 |
| 546.58 | 7.73 | 7.73 |
| 532.55 | 6.87 | 6.87 |
| 492.87 | 6.67 | 6.67 |