Assay Report Card

Basic Information

ID: ALA5165083

Type: Functional

Description: In vivo inhibition of cathepsin C in po dosed LPS-induced ALI C57BL/6 mouse model assessed as downregulation of neutrophil elastase activity in blood treated 1 hr prior to LPS challenge and measured after 48 hrs

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
436.935.705.70