Basic Information
ID: ALA5165168
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes at 10 uM incubated for 10 mins in presence of NADPH by LC-MS/MS analysis relative to control
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Cytochrome P450 3A4(ALA340)
Document: ALA5154874
Inhibition of CYP3A4 in human liver microsomes at 10 uM incubated for 10 mins in presence of NADPH by LC-MS/MS analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5165168
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.54 | 4.03 | 4.03 |
| 532.13 | 8.44 | 8.44 |
| 637.29 | 10.16 | 10.16 |