Basic Information
ID: ALA5165207
Type: Binding
Description: Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells assessed as inhibition constant using 10-mer-Thr-FAM peptide as substrate incubated for 1 hr by Lantha Screen based TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5165207
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 511.63 | 4.25 | 4.25 |
| 550.59 | 5.39 | 5.39 |
| 550.59 | 5.39 | 5.39 |
| 565.60 | 5.44 | 5.44 |
| 530.60 | 4.38 | 4.38 |
| 494.52 | 4.56 | 4.56 |
| 516.57 | 4.08 | 4.08 |
| 575.54 | 5.50 | 5.50 |
| 508.55 | 4.82 | 4.82 |
| 551.57 | 4.65 | 4.65 |
| 538.57 | 5.31 | 5.31 |
| 510.52 | 4.26 | 4.26 |
| 524.55 | 5.00 | 5.00 |
| 538.57 | 5.31 | 5.31 |
| 500.60 | 3.28 | 3.28 |
| 513.60 | 3.64 | 3.64 |
| 497.60 | 3.94 | 3.94 |
| 524.55 | 4.74 | 4.74 |
| 525.53 | 4.57 | 4.57 |
| 500.60 | 3.28 | 3.28 |
| 494.52 | 4.56 | 4.56 |
| 526.52 | 3.96 | 3.96 |
| 494.52 | 4.56 | 4.56 |
| 568.60 | 4.47 | 4.47 |
| 548.61 | 6.00 | 6.00 |
| 522.58 | 5.30 | 5.30 |
| 553.59 | 5.13 | 5.13 |
| 494.52 | 4.56 | 4.56 |
| 525.53 | 4.57 | 4.57 |
| 564.61 | 5.70 | 5.70 |
| 511.63 | 4.25 | 4.25 |
| 514.63 | 3.59 | 3.59 |
| 554.57 | 3.99 | 3.99 |
| 524.54 | 5.17 | 5.17 |
| 567.61 | 5.69 | 5.69 |
| 539.56 | 4.87 | 4.87 |
| 497.60 | 3.94 | 3.94 |
| 487.56 | 3.53 | 3.53 |
| 480.49 | 4.25 | 4.25 |