Basic Information
ID: ALA5165218
Type: Binding
Description: Negative allosteric modulation activity against human ATX using FS-3 as substrate preincubated for 45 mins followed by substrate addition and measured every 30 mins by multi-mode microplate reader
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5165218
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 478.33 | 3.96 | 3.96 |
| 588.71 | 3.43 | 3.43 |
| 502.59 | 5.59 | 5.59 |
| 549.07 | 6.12 | 6.12 |
| 565.55 | 8.16 | 8.16 |
| 527.45 | 6.01 | 6.01 |
| 547.65 | 6.04 | 6.04 |
| 596.56 | 6.04 | 6.04 |
| 566.53 | 6.68 | 6.68 |
| 595.67 | 5.75 | 5.75 |
| 551.52 | 7.91 | 7.91 |
| 516.62 | 5.72 | 5.72 |
| 567.52 | 6.88 | 6.88 |
| 569.56 | 7.48 | 7.48 |
| 571.51 | 5.71 | 5.71 |
| 567.52 | 6.88 | 6.88 |
| 565.64 | 6.39 | 6.39 |
| 545.66 | 4.87 | 4.87 |
| 537.49 | 7.52 | 7.52 |
| 536.65 | 6.45 | 6.45 |
| 553.49 | 6.76 | 6.76 |
| 563.65 | 5.01 | 5.01 |
| 533.62 | 5.65 | 5.65 |
| 579.67 | 6.78 | 6.78 |
| 451.47 | 5.39 | 5.39 |