Assay Report Card

Basic Information

ID: ALA5165879

Type: Functional

Description: Antitumor activity against mouse EMT6 cells implanted in BALB/c mouse syngenic model assessed as downregulation of p-retinoblastoma level in tumor at 20 to 40 mg/kg, po qd measured after 18 days by immunohistochemical analysis

Organism: Mus musculus

Strain: BALB/c

Cell type: EMT6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
693.236.736.73