Basic Information
ID: ALA5166005
Type: Binding
Description: Inhibition of eGFP-tagged rat GluN1/GluN2A transfected in human tsA201 cells assessed as blockade of glycine/NMDA-induced current at 10 uM treated for 40 secs measured at -60 mV holding potential after returning from +60 mV application for 5 secs by whole-cell patch-clamp method relative to control
Organism: Rattus norvegicus
Cell type: tsA201
Activity Charts
Bioactivity
Activity Types for Assay ALA5166005
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 179.31 | 2.69 | 2.69 |
| 226.34 | 3.16 | 3.16 |
| 243.32 | 3.25 | 3.25 |
| 225.33 | 3.16 | 3.16 |