Assay Report Card

Basic Information

ID: ALA5166008

Type: Binding

Description: Inhibition of eGFP-tagged rat GluN1/GluN2A transfected in human tsA201 cells assessed as recovery of glycine/NMDA-induced current at 10 uM treated for 40 secs followed by application of +60 mV holding potential for 5 secs measured after 40 secs of compound removal by whole-cell patch-clamp method relative to control

Organism: Rattus norvegicus

Cell type: tsA201

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
179.312.692.69
243.323.253.25
225.333.163.16