Basic Information
ID: ALA5166506
Type: ADME
Description: Apparent permeability across basolateral to apical side in dog MDCKII-MDR1 cells at 3 uM preincubated with P-gp inhibitor elacridar for 15 to 30 mins followed by compound addition and measured after 60 to 90 mins by LC-MS/MS analysis
Organism: Canis lupus familiaris
Cell type: MDCK-MDR1
Activity Charts
Bioactivity
Activity Types for Assay ALA5166506
Papp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.15 | 4.07 | 4.07 |