Assay Report Card

Basic Information

ID: ALA5166508

Type: ADME

Description: Efflux ratio of apparent permeability from basolateral to apical side over apical to basolateral side in dog MDCK-II cells expressing BCRP at 3 uM preincubated with BCRP inhibitor, Ko 143 for 15 to 30 mins followed by compound addition and measured after 60 to 90 mins by LC-MS/MS analysis

Organism: Canis lupus familiaris

Cell type: MDCK-II

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
312.154.074.07