ID: ALA5166508
Type: ADME
Description: Efflux ratio of apparent permeability from basolateral to apical side over apical to basolateral side in dog MDCK-II cells expressing BCRP at 3 uM preincubated with BCRP inhibitor, Ko 143 for 15 to 30 mins followed by compound addition and measured after 60 to 90 mins by LC-MS/MS analysis
Organism: Canis lupus familiaris
Cell type: MDCK-II
Bioactivity
Activity Types for Assay ALA5166508
Ratio
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
312.15 | 4.07 | 4.07 |