Assay Report Card

Basic Information

ID: ALA5166510

Type: ADME

Description: Efflux ratio of apparent permeability from basolateral to apical side over apical to basolateral side in dog MDCKII-MDR1 cells at 3 uM preincubated with P-gp inhibitor, elacridar for 15 to 30 mins followed by compound addition and measured after 60 to 90 mins by LC-MS/MS analysis

Organism: Canis lupus familiaris

Cell type: MDCK-MDR1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
312.154.074.07