Basic Information
ID: ALA5166570
Type: Binding
Description: Displacement of fluorescein-labeled JQ1 from His6/TEV cleavage site fused human BRD4 (residues N44 to E168) expressed in Escherichia coli BL21 (DE3) incubated for 60 min by Fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5166570
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.00 | 5.53 | 5.53 |
| 998.69 | 10.11 | 10.11 |
| 899.56 | 8.76 | 8.76 |
| 1012.72 | ||
| 1074.75 | ||
| 986.64 | 7.97 | 7.97 |
| 929.59 | 8.99 | 8.99 |
| 915.56 | 8.60 | 8.60 |
| 957.64 | 9.77 | 9.77 |
| 885.53 | 8.72 | 8.72 |
| 943.61 | 9.38 | 9.38 |
| 871.51 | 9.04 | 9.04 |