Basic Information
ID: ALA5166788
Type: Binding
Description: Agonist activity at human TR beta LBD (202 to 461 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as induction of N-terminal biotinylated coactivator SRC2-3 peptide recruitment by alphascreen assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Thyroid hormone receptor beta-1(ALA1947)
Document: ALA5154903
Agonist activity at human TR beta LBD (202 to 461 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as induction of N-terminal biotinylated coactivator SRC2-3 peptide recruitment by alphascreen assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5166788
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 650.98 | 3.95 | 3.95 |
| 352.35 | 2.86 | 2.86 |
| 435.23 | 2.10 | 2.10 |
| 372.76 | 3.20 | 3.20 |
| 444.44 | 4.22 | 4.22 |
| 395.42 | 2.61 | 2.61 |
| 368.35 | 2.56 | 2.56 |
| 382.37 | 2.95 | 2.95 |
| 514.53 | 4.71 | 4.71 |
| 458.47 | 4.15 | 4.15 |
| 500.51 | 4.40 | 4.40 |
| 528.56 | 5.10 | 5.10 |
| 472.45 | 3.79 | 3.79 |
| 472.50 | 4.54 | 4.54 |
| 472.50 | 4.34 | 4.34 |
| 562.55 | 4.94 | 4.94 |
| 458.47 | 4.61 | 4.61 |
| 486.52 | 4.76 | 4.76 |
| 486.52 | 4.88 | 4.88 |
| 474.47 | 4.74 | 4.74 |
| 458.47 | 4.15 | 4.15 |
| 472.50 | 4.54 | 4.54 |
| 548.52 | 4.55 | 4.55 |
| 542.59 | 5.41 | 5.41 |
| 436.46 | 4.26 | 4.26 |
| 528.56 | 5.02 | 5.02 |
| 412.40 | 2.57 | 2.57 |
| 486.48 | 4.18 | 4.18 |
| 460.44 | 4.35 | 4.35 |
| 408.41 | 3.48 | 3.48 |
| 422.44 | 3.87 | 3.87 |
| 417.21 | 3.31 | 3.31 |