Basic Information
ID: ALA5166901
Type: Binding
Description: Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by fluorescence based assay
Organism: Homo sapiens
Cell type: HEK293S
Activity Charts
Bioactivity
Activity Types for Assay ALA5166901
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 175.19 | 0.76 | 0.76 |
| 209.64 | 1.41 | 1.41 |
| 209.64 | 1.41 | 1.41 |
| 209.64 | 1.41 | 1.41 |
| 189.22 | 1.07 | 1.07 |
| 244.08 | 2.07 | 2.07 |
| 244.08 | 2.07 | 2.07 |
| 244.08 | 2.07 | 2.07 |
| 200.20 | 0.63 | 0.63 |
| 200.20 | 0.63 | 0.63 |
| 340.13 | 3.52 | 3.52 |
| 219.24 | 1.16 | 1.16 |
| 282.05 | 3.59 | 3.59 |
| 219.20 | 0.49 | 0.49 |
| 326.11 | 3.74 | 3.74 |
| 283.04 | 2.99 | 2.99 |
| 312.08 | 3.09 | 3.09 |
| 244.08 | 2.07 | 2.07 |
| 277.63 | 2.43 | 2.43 |
| 193.18 | 0.90 | 0.90 |
| 282.05 | 3.59 | 3.59 |
| 326.06 | 3.29 | 3.29 |
| 193.18 | 0.90 | 0.90 |
| 277.63 | 2.43 | 2.43 |
| 311.09 | 3.05 | 3.05 |
| 340.13 | 3.52 | 3.52 |
| 219.24 | 1.16 | 1.16 |
| 325.08 | 2.69 | 2.69 |
| 243.19 | 1.78 | 1.78 |
| 296.08 | 3.90 | 3.90 |
| 283.04 | 2.99 | 2.99 |
| 243.19 | 1.78 | 1.78 |
| 326.11 | 3.13 | 3.13 |
| 368.14 | 2.90 | 2.90 |
| 311.18 | 2.80 | 2.80 |
| 244.08 | 2.07 | 2.07 |
| 339.10 | 2.95 | 2.95 |
| 326.11 | 3.65 | 3.65 |
| 233.23 | 0.53 | 0.53 |
| 203.25 | 1.38 | 1.38 |
| 284.06 | 3.59 | 3.59 |
| 248.50 | 3.23 | 3.23 |