Basic Information
ID: ALA5167049
Type: Binding
Description: Inhibition of recombinant full length His tagged human CDK8/Cyclin C expressed in Baculovirus at 200 nM incubated for 60 mins in presence of ATP by ADP-Glo kinase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5167049
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.90 | 3.70 | 3.70 |
| 414.51 | 2.77 | 2.77 |
| 328.37 | 5.14 | 5.14 |
| 419.46 | 3.50 | 3.50 |
| 400.48 | 2.72 | 2.72 |
| 426.52 | 4.97 | 4.97 |
| 419.46 | 3.50 | 3.50 |
| 371.39 | 4.79 | 4.79 |
| 342.39 | 5.40 | 5.40 |
| 485.46 | 4.26 | 4.26 |
| 386.46 | 3.05 | 3.05 |
| 454.53 | 4.61 | 4.61 |
| 401.47 | 3.36 | 3.36 |
| 470.45 | 3.94 | 3.94 |
| 401.47 | 2.63 | 2.63 |
| 385.47 | 3.65 | 3.65 |
| 404.42 | 4.86 | 4.86 |
| 426.47 | 3.88 | 3.88 |
| 412.49 | 4.58 | 4.58 |
| 454.45 | 4.07 | 4.07 |
| 414.51 | 3.61 | 3.61 |
| 386.46 | 3.05 | 3.05 |
| 440.50 | 4.22 | 4.22 |
| 401.47 | 2.63 | 2.63 |
| 443.52 | 5.02 | 5.02 |
| 431.49 | 3.37 | 3.37 |
| 398.46 | 4.24 | 4.24 |
| 348.79 | 5.49 | 5.49 |
| 401.47 | 2.63 | 2.63 |
| 454.45 | 4.07 | 4.07 |
| 316.32 | 3.62 | 3.62 |
| 386.46 | 3.05 | 3.05 |
| 469.46 | 4.38 | 4.38 |
| 428.54 | 4.17 | 4.17 |
| 443.55 | 4.48 | 4.48 |
| 443.55 | 4.48 | 4.48 |
| 416.48 | 2.94 | 2.94 |
| 416.48 | 3.05 | 3.05 |
| 458.52 | 3.32 | 3.32 |
| 400.48 | 3.35 | 3.35 |
| 404.45 | 3.19 | 3.19 |
| 443.55 | 4.28 | 4.28 |
| 401.47 | 2.63 | 2.63 |
| 320.37 | 4.89 | 4.89 |
| 357.41 | 4.90 | 4.90 |
| 428.54 | 4.17 | 4.17 |
| 420.90 | 3.70 | 3.70 |
| 404.42 | 4.86 | 4.86 |
| 428.54 | 4.17 | 4.17 |
| 416.48 | 3.05 | 3.05 |
| 443.51 | 3.00 | 3.00 |
| 416.48 | 2.94 | 2.94 |
| 485.46 | 4.26 | 4.26 |
| 470.45 | 3.94 | 3.94 |
| 427.46 | 4.31 | 4.31 |
| 443.51 | 3.00 | 3.00 |
| 401.47 | 2.63 | 2.63 |
| 458.52 | 3.32 | 3.32 |
| 400.48 | 3.35 | 3.35 |
| 382.34 | 5.85 | 5.85 |
| 429.52 | 3.92 | 3.92 |
| 431.49 | 3.37 | 3.37 |
| 443.51 | 3.00 | 3.00 |
| 385.42 | 4.53 | 4.53 |
| 314.34 | 4.83 | 4.83 |
| 401.47 | 3.36 | 3.36 |
| 415.49 | 3.67 | 3.67 |
| 416.48 | 3.05 | 3.05 |
| 419.46 | 3.50 | 3.50 |
| 413.47 | 4.66 | 4.66 |
| 443.55 | 4.48 | 4.48 |
| 404.45 | 3.19 | 3.19 |
| 469.46 | 4.38 | 4.38 |
| 401.47 | 3.36 | 3.36 |
| 414.51 | 3.61 | 3.61 |
| 442.56 | 4.34 | 4.34 |
| 404.45 | 3.19 | 3.19 |
| 344.37 | 4.84 | 4.84 |
| 398.34 | 5.73 | 5.73 |
| 392.50 | 2.86 | 2.86 |
| 304.30 | 4.43 | 4.43 |
| 400.48 | 3.35 | 3.35 |
| 315.33 | 4.23 | 4.23 |
| 333.34 | 4.44 | 4.44 |
| 399.45 | 4.67 | 4.67 |
| 457.57 | 4.65 | 4.65 |
| 468.55 | 5.00 | 5.00 |
| 329.36 | 4.41 | 4.41 |
| 390.44 | 2.32 | 2.32 |
| 318.33 | 3.57 | 3.57 |
| 415.49 | 3.67 | 3.67 |
| 426.52 | 4.58 | 4.58 |
| 371.44 | 4.89 | 4.89 |
| 412.49 | 4.24 | 4.24 |
| 414.51 | 3.61 | 3.61 |