Basic Information
ID: ALA5167053
Type: Binding
Description: Inhibition of human recombinant full length GST-tagged p38alpha expressed in Escherichia coli preincubated for 2 hrs followed by ATP addition and measured after 1 hr by Alpha screen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5167053
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 634.79 | 6.26 | 6.26 |
| 614.15 | 7.47 | 7.47 |
| 577.73 | 7.42 | 7.42 |
| 691.88 | 6.92 | 6.92 |
| 693.90 | 6.51 | 6.51 |
| 701.92 | 7.97 | 7.97 |
| 617.80 | 8.35 | 8.35 |
| 735.94 | 6.29 | 6.29 |
| 563.71 | 7.11 | 7.11 |
| 634.78 | 6.47 | 6.47 |
| 618.79 | 7.29 | 7.29 |
| 716.93 | 6.73 | 6.73 |
| 706.90 | 6.70 | 6.70 |
| 706.90 | 6.70 | 6.70 |
| 734.95 | 5.81 | 5.81 |
| 707.88 | 6.10 | 6.10 |
| 723.93 | 6.14 | 6.14 |
| 760.99 | 6.99 | 6.99 |
| 623.76 | 6.48 | 6.48 |
| 719.93 | 7.70 | 7.70 |
| 735.94 | 6.02 | 6.02 |
| 702.91 | 6.38 | 6.38 |
| 648.81 | 6.51 | 6.51 |
| 501.64 | 5.66 | 5.66 |
| 693.90 | 6.52 | 6.52 |
| 679.87 | 6.13 | 6.13 |
| 729.97 | 8.03 | 8.03 |
| 603.77 | 7.96 | 7.96 |
| 604.76 | 6.90 | 6.90 |
| 650.78 | 5.44 | 5.44 |
| 721.91 | 5.90 | 5.90 |
| 679.87 | 6.13 | 6.13 |
| 746.96 | 7.99 | 7.99 |
| 655.20 | 7.34 | 7.34 |
| 705.91 | 7.31 | 7.31 |
| 529.69 | 6.16 | 6.16 |
| 633.80 | 6.05 | 6.05 |
| 577.73 | 7.42 | 7.42 |
| 614.15 | 7.47 | 7.47 |
| 650.83 | 7.05 | 7.05 |
| 726.33 | 7.57 | 7.57 |
| 620.76 | 6.13 | 6.13 |
| 705.91 | 7.31 | 7.31 |