Assay Report Card

Basic Information

ID: ALA5167109

Type: Binding

Description: Irreversible inhibition of FGFR4 signalling in human Huh-7 cells assessed as inhibition of ERK1/2 phosphorylation at 30 nM preincubated for 1 hr followed by compound washout with PBS and stimulated with FGF19 for 10 mins by Western blot analysis

Organism: Homo sapiens

Cell type: Huh-7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
527.584.524.52