Basic Information
ID: ALA5167326
Type: Toxicity
Description: Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp method
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA5167326
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.44 | 4.55 | 4.55 |
| 485.54 | 3.34 | 3.34 |
| 410.45 | 3.80 | 3.80 |
| 423.44 | 3.55 | 3.55 |
| 452.49 | 3.57 | 3.57 |
| 434.43 | 3.95 | 3.95 |
| 436.49 | 4.34 | 4.34 |
| 367.38 | 2.55 | 2.55 |
| 499.56 | 3.47 | 3.47 |
| 437.47 | 3.94 | 3.94 |
| 437.47 | 3.68 | 3.68 |
| 407.45 | 2.98 | 2.98 |
| 452.49 | 2.55 | 2.55 |
| 353.35 | 3.05 | 3.05 |
| 459.50 | 2.69 | 2.69 |
| 407.45 | 4.06 | 4.06 |
| 459.50 | 2.81 | 2.81 |
| 437.48 | 2.61 | 2.61 |
| 421.47 | 4.45 | 4.45 |
| 451.50 | 4.07 | 4.07 |
| 459.50 | 1.73 | 1.73 |
| 437.47 | 3.83 | 3.83 |
| 479.52 | 1.99 | 1.99 |
| 395.44 | 2.98 | 2.98 |
| 434.43 | 3.95 | 3.95 |
| 437.48 | 2.75 | 2.75 |
| 473.53 | 3.08 | 3.08 |
| 381.41 | 3.67 | 3.67 |
| 464.50 | 2.05 | 2.05 |
| 381.41 | 2.59 | 2.59 |
| 367.38 | 3.39 | 3.39 |
| 395.43 | 4.17 | 4.17 |
| 450.51 | 4.73 | 4.73 |