Basic Information
ID: ALA5167410
Type: Binding
Description: Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells assessed as maximal efficacy at 5 uM in presence of BAM8-22 by Fluo4-dye based FLIPR assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5167410
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.85 | 4.44 | 4.44 |
| 360.44 | 3.24 | 3.24 |
| 432.40 | 3.92 | 3.92 |
| 366.41 | 3.24 | 3.24 |
| 394.88 | 3.90 | 3.90 |
| 356.45 | 3.18 | 3.18 |
| 378.43 | 3.38 | 3.38 |
| 378.43 | 3.38 | 3.38 |
| 382.87 | 3.75 | 3.75 |
| 386.47 | 3.63 | 3.63 |
| 432.40 | 3.92 | 3.92 |
| 420.38 | 3.78 | 3.78 |
| 380.44 | 3.55 | 3.55 |
| 360.44 | 3.24 | 3.24 |
| 428.43 | 4.09 | 4.09 |
| 436.84 | 4.30 | 4.30 |
| 357.44 | 3.52 | 3.52 |
| 361.42 | 2.64 | 2.64 |
| 361.42 | 2.64 | 2.64 |
| 404.49 | 3.64 | 3.64 |
| 410.50 | 4.39 | 4.39 |
| 374.46 | 2.92 | 2.92 |
| 412.87 | 4.03 | 4.03 |
| 372.45 | 3.17 | 3.17 |
| 358.42 | 2.91 | 2.91 |
| 414.40 | 3.78 | 3.78 |
| 416.42 | 3.95 | 3.95 |
| 396.37 | 3.16 | 3.16 |
| 420.38 | 3.78 | 3.78 |
| 385.45 | 3.71 | 3.71 |
| 400.86 | 3.89 | 3.89 |
| 374.46 | 3.63 | 3.63 |
| 360.44 | 3.24 | 3.24 |
| 370.43 | 3.90 | 3.90 |
| 374.42 | 2.61 | 2.61 |
| 374.46 | 3.63 | 3.63 |
| 357.44 | 3.53 | 3.53 |
| 392.45 | 3.69 | 3.69 |
| 396.42 | 3.52 | 3.52 |
| 410.50 | 4.39 | 4.39 |
| 366.48 | 2.67 | 2.67 |
| 388.45 | 3.35 | 3.35 |
| 374.46 | 3.55 | 3.55 |
| 360.44 | 2.88 | 2.88 |
| 358.42 | 2.63 | 2.63 |
| 394.88 | 3.90 | 3.90 |
| 366.41 | 3.24 | 3.24 |
| 362.45 | 3.41 | 3.41 |
| 378.43 | 3.38 | 3.38 |
| 390.46 | 2.87 | 2.87 |
| 384.40 | 3.38 | 3.38 |
| 358.42 | 2.91 | 2.91 |
| 360.39 | 2.57 | 2.57 |
| 346.41 | 2.85 | 2.85 |
| 374.42 | 2.61 | 2.61 |
| 400.50 | 4.16 | 4.16 |
| 361.42 | 2.64 | 2.64 |
| 378.43 | 3.38 | 3.38 |
| 384.46 | 3.44 | 3.44 |
| 374.46 | 3.55 | 3.55 |
| 356.40 | 3.59 | 3.59 |