Basic Information
ID: ALA5167479
Type: Binding
Description: Autophagosome tethering activity at NMAPT overexpressing human A2780 cells assessed as lysosome-mediated degradation of NAMPT by measuring blockage of LC3 at 1 uM pretreated with probe N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-N-(3-(3-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)thioureido)propyl)-4-methylbenzamide followed by addition of compound measured after 48 hrs by western blot analysis
Organism: Homo sapiens
Cell type: A2780
Activity Charts
Bioactivity
Activity Types for Assay ALA5167479
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1046.80 |