Basic Information
ID: ALA5167770
Type: ADME
Description: Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate incubated for 5 to 45 mins in presence of NADPH by LC/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5167770
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 586.20 | 8.95 | 8.95 |
| 386.50 | 3.17 | 3.17 |
| 469.36 | 3.72 | 3.72 |