Basic Information
ID: ALA5167930
Type: Functional
Description: In vivo inhibition of PRMT5 in human A-375 cells xenografted in BALB/c mouse assessed as reduction in H4R3me2s levels in tumor tissue at 75 mg/kg, po qd for 19 days measured after 3 weeks by Western blot analysis
Organism: Mus musculus
Strain: BALB/c
Activity Charts
Bioactivity
Activity Types for Assay ALA5167930
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.49 | 5.14 | 5.14 |