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Poison activity at human topoisomerase II-alpha assessed as stabilization of enzyme-DNA cleavage complex by measuring nicked DNA formation at 100 uM a...

Basic Information

ID: ALA5167959

Type: Binding

Description: Poison activity at human topoisomerase II-alpha assessed as stabilization of enzyme-DNA cleavage complex by measuring nicked DNA formation at 100 uM after 60 mins by agarose gel electrophoresis method

Format: BAO_0000357

Organism: Homo sapiens

Target:  DNA topoisomerase II alpha(ALA1806)

Document:  ALA5154929

Poison activity at human topoisomerase II-alpha assessed as stabilization of enzyme-DNA cleavage complex by measuring nicked DNA formation at 100 uM after 60 mins by agarose gel electrophoresis method: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
468.563.233.23
369.432.132.13
511.491.481.48