Potency index, ratio of (S)-N-((S)-1-((S)-3-amino-1-((S)-1-((S)-2-(1-(cyclohexylmethyl)-4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-cyclopentyl-1-oxo...

Basic Information

ID: ALA5168040

Type: Functional

Description: Potency index, ratio of (S)-N-((S)-1-((S)-3-amino-1-((S)-1-((S)-2-(1-(cyclohexylmethyl)-4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-cyclopentyl-1-oxopropan-2-ylamino)-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-yl)-1-(4-methylpentanoyl)pyrrolidine-2-carboxamide IC50 to test compound IC50 for anticancer activity against human KOPN-8 cells

Format: BAO_0000219

Organism: Homo sapiens

Cell type: KOPN-8

Target:  KOPN-8(ALA4296456)

Document:  ALA5154930

Potency index, ratio of (S)-N-((S)-1-((S)-3-amino-1-((S)-1-((S)-2-(1-(cyclohexylmethyl)-4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-cyclopentyl-1-oxopropan-2-ylamino)-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-yl)-1-(4-methylpentanoyl)pyrrolidine-2-carboxamide IC50 to test compound IC50 for anticancer activity against human KOPN-8 cells: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
842.104.234.23
890.144.824.82
856.134.624.62
840.084.084.08
814.043.603.60
856.134.624.62