Basic Information
ID: ALA5168095
Type: Functional
Description: Cytotoxicity against multidrug resistance human MES-SA/Dx5 cells assessed as cell growth inhibition incubated for 72 hrs in presence of P-gp inhibitor Tariquidar by PrestoBlue reagent based cell viability assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MES-SA/Dx5
Target: MES-SA/Dx5(ALA613827)
Document: ALA5154931
Cytotoxicity against multidrug resistance human MES-SA/Dx5 cells assessed as cell growth inhibition incubated for 72 hrs in presence of P-gp inhibitor Tariquidar by PrestoBlue reagent based cell viability assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5168095
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 145.16 | 1.94 | 1.94 |
| 321.22 | 3.69 | 3.69 |
| 242.32 | 2.93 | 2.93 |
| 296.75 | 1.38 | 1.38 |
| 272.35 | 2.68 | 2.68 |
| 291.78 | 2.34 | 2.34 |
| 301.39 | 1.83 | 1.83 |
| 371.84 | 4.06 | 4.06 |
| 353.85 | 4.56 | 4.56 |
| 324.81 | 4.15 | 4.15 |
| 391.52 | 4.19 | 4.19 |
| 354.84 | 3.31 | 3.31 |
| 353.85 | 3.92 | 3.92 |
| 343.47 | 3.00 | 3.00 |
| 230.31 | 2.78 | 2.78 |
| 228.29 | 2.54 | 2.54 |
| 276.77 | 3.58 | 3.58 |
| 348.83 | 3.37 | 3.37 |
| 321.38 | 2.76 | 2.76 |
| 352.87 | 5.09 | 5.09 |
| 286.38 | 3.07 | 3.07 |
| 333.44 | 3.57 | 3.57 |
| 315.42 | 2.22 | 2.22 |
| 334.42 | 2.67 | 2.67 |
| 329.44 | 2.61 | 2.61 |
| 257.34 | 1.69 | 1.69 |
| 262.74 | 3.19 | 3.19 |
| 391.52 | 4.19 | 4.19 |
| 377.49 | 3.80 | 3.80 |
| 288.35 | 1.92 | 1.92 |
| 328.46 | 4.10 | 4.10 |
| 363.46 | 3.41 | 3.41 |
| 348.45 | 3.06 | 3.06 |
| 286.37 | 3.07 | 3.07 |
| 290.79 | 3.97 | 3.97 |
| 319.41 | 3.91 | 3.91 |
| 314.43 | 3.85 | 3.85 |
| 290.79 | 3.83 | 3.83 |
| 314.43 | 3.85 | 3.85 |
| 374.92 | 3.33 | 3.33 |
| 290.79 | 3.97 | 3.97 |
| 369.26 | 4.26 | 4.26 |
| 290.37 | 3.50 | 3.50 |
| 307.19 | 3.30 | 3.30 |
| 300.40 | 3.32 | 3.32 |
| 323.19 | 2.54 | 2.54 |
| 348.83 | 3.37 | 3.37 |
| 264.76 | 3.44 | 3.44 |
| 300.40 | 3.46 | 3.46 |
| 314.43 | 3.71 | 3.71 |
| 339.83 | 4.17 | 4.17 |