Potentiation of antifungal activity against fluconazole-sensitive Candida albicans YEM12 overexpressing efflux pump MDR1 gene assessed as fold reducti...

Basic Information

ID: ALA5168190

Type: Functional

Description: Potentiation of antifungal activity against fluconazole-sensitive Candida albicans YEM12 overexpressing efflux pump MDR1 gene assessed as fold reduction in fluconazole MIC at 1 ug/ml incubated for 24 hrs by checkerboard broth microdilution assay

Format: BAO_0000218

Organism: Candida albicans

Strain: YEM12

Target:  Candida albicans(ALA366)

Document:  ALA5154933

Potentiation of antifungal activity against fluconazole-sensitive Candida albicans YEM12 overexpressing efflux pump MDR1 gene assessed as fold reduction in fluconazole MIC at 1 ug/ml incubated for 24 hrs by checkerboard broth microdilution assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
630.924.084.08