Basic Information
ID: ALA5168261
Type: Binding
Description: Inhibition of Top1 (unknown origin) assessed as inhibition of relaxation of supercoiled pBR322 plasmid DNA at 12.5 uM incubated for 25 mins by ethidium bromide staining based agarose gel electrophoresis analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5168261
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 303.36 | 3.31 | 3.31 |
| 419.41 | 5.43 | 5.43 |
| 453.85 | 6.09 | 6.09 |
| 449.43 | 5.44 | 5.44 |
| 477.44 | 5.36 | 5.36 |
| 463.46 | 5.83 | 5.83 |
| 435.41 | 5.14 | 5.14 |
| 433.43 | 5.74 | 5.74 |