Basic Information
ID: ALA5168262
Type: Binding
Description: Inhibition of human Top2-alpha expressed in baculovirus assessed as inhibition of relaxation of supercoiled pBR322 plasmid DNA at 100 uM incubated for 30 mins in presence of ATP by ethidium bromide staining based agarose gel electrophoresis analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5168262
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 303.36 | 3.31 | 3.31 |
| 419.41 | 5.43 | 5.43 |
| 453.85 | 6.09 | 6.09 |
| 449.43 | 5.44 | 5.44 |
| 477.44 | 5.36 | 5.36 |
| 463.46 | 5.83 | 5.83 |
| 435.41 | 5.14 | 5.14 |
| 433.43 | 5.74 | 5.74 |