Basic Information
ID: ALA5168879
Type: ADME
Description: Microsomal stability in CD1 mouse liver microsomes assessed as half life measured upto 60 mins in presence of NADPH by LC-MS analysis
Organism: Mus musculus
Strain: CD1
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5168879
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.44 | 5.32 | 5.32 |
| 434.54 | 5.08 | 5.08 |
| 420.52 | 4.69 | 4.69 |
| 474.61 | 6.18 | 6.18 |
| 376.50 | 3.79 | 3.79 |
| 510.64 | 6.99 | 6.99 |
| 474.61 | 5.93 | 5.93 |
| 539.66 | 4.70 | 4.70 |
| 510.64 | 6.48 | 6.48 |
| 578.76 | 6.91 | 6.91 |
| 534.66 | 6.19 | 6.19 |
| 474.61 | 6.13 | 6.13 |
| 504.63 | 6.18 | 6.18 |
| 474.61 | 6.18 | 6.18 |
| 544.58 | 6.95 | 6.95 |
| 390.53 | 3.91 | 3.91 |
| 502.66 | 6.50 | 6.50 |
| 464.57 | 5.09 | 5.09 |
| 447.59 | 5.26 | 5.26 |
| 520.68 | 6.88 | 6.88 |
| 474.61 | 6.07 | 6.07 |
| 548.60 | 5.51 | 5.51 |
| 513.62 | 3.73 | 3.73 |
| 518.54 | 5.98 | 5.98 |
| 488.64 | 6.37 | 6.37 |
| 440.59 | 5.61 | 5.61 |
| 540.67 | 6.96 | 6.96 |
| 438.58 | 5.49 | 5.49 |
| 450.54 | 4.70 | 4.70 |
| 475.64 | 5.85 | 5.85 |
| 460.58 | 5.74 | 5.74 |
| 336.44 | 3.33 | 3.33 |
| 424.55 | 5.41 | 5.41 |
| 490.61 | 5.89 | 5.89 |
| 502.66 | 6.45 | 6.45 |
| 558.60 | 7.07 | 7.07 |
| 549.72 | 7.54 | 7.54 |
| 553.69 | 4.77 | 4.77 |
| 434.54 | 4.89 | 4.89 |
| 488.64 | 6.25 | 6.25 |
| 460.58 | 5.88 | 5.88 |
| 310.40 | 2.36 | 2.36 |
| 480.66 | 6.71 | 6.71 |
| 384.48 | 4.38 | 4.38 |
| 448.57 | 5.47 | 5.47 |
| 480.57 | 4.71 | 4.71 |
| 534.66 | 6.19 | 6.19 |
| 472.59 | 6.38 | 6.38 |
| 419.53 | 4.66 | 4.66 |
| 474.61 | 6.53 | 6.53 |
| 462.60 | 5.86 | 5.86 |
| 474.61 | 6.29 | 6.29 |
| 490.61 | 6.06 | 6.06 |
| 398.51 | 4.44 | 4.44 |
| 520.63 | 5.75 | 5.75 |
| 558.60 | 7.07 | 7.07 |
| 460.58 | 6.05 | 6.05 |
| 494.60 | 5.10 | 5.10 |
| 548.69 | 6.85 | 6.85 |
| 344.42 | 3.02 | 3.02 |
| 350.47 | 2.82 | 2.82 |
| 380.45 | 4.67 | 4.67 |
| 466.63 | 6.58 | 6.58 |
| 520.63 | 6.07 | 6.07 |
| 461.61 | 5.65 | 5.65 |
| 405.50 | 6.44 | 6.44 |
| 350.47 | 3.46 | 3.46 |
| 474.61 | 6.18 | 6.18 |
| 488.64 | 6.32 | 6.32 |
| 504.63 | 6.13 | 6.13 |
| 464.57 | 5.29 | 5.29 |
| 434.54 | 5.35 | 5.35 |
| 474.61 | 6.25 | 6.25 |
| 572.63 | 7.73 | 7.73 |
| 446.55 | 5.35 | 5.35 |
| 496.62 | 6.21 | 6.21 |
| 488.64 | 6.83 | 6.83 |
| 434.54 | 5.61 | 5.61 |
| 462.60 | 5.67 | 5.67 |